Mechanisms underlying smooth muscle Ca 2+ waves in cremaster muscle arterioles
نویسندگان
چکیده
منابع مشابه
Asynchronous Ca(2+) waves in intact venous smooth muscle.
The rabbit inferior vena cava (IVC) is a large-capacitance vessel that displays typical contractile dose-response curves for caffeine and phenylephrine (PE). Using confocal microscopy on the endothelium-denuded IVC, we undertook experiments to correlate these whole-tissue contractile dose-response curves with changes in subcellular [Ca(2+)](i) signals in the in situ vascular smooth muscle cells...
متن کاملMyogenic contraction in rat skeletal muscle arterioles: smooth muscle membrane potential and Ca(2+) signaling.
The present studies examined relationships between intraluminal pressure, membrane potential (E(m)), and myogenic tone in skeletal muscle arterioles. Using pharmacological interventions targeting Ca(2+) entry/release mechanisms, these studies also determined the role of Ca(2+) pathways and E(m) in determining steady-state myogenic constriction. Studies were conducted in isolated and cannulated ...
متن کاملMyogenic contraction in rat skeletal muscle arterioles: smooth muscle membrane potential and Ca signaling
Kotecha, Neela, and Michael A. Hill. Myogenic contraction in rat skeletal muscle arterioles: smooth muscle membrane potential and Ca signaling. Am J Physiol Heart Circ Physiol 289: H1326–H1334, 2005. First published April 29, 2005; doi:10.1152/ajpheart.00323.2005.—The present studies examined relationships between intraluminal pressure, membrane potential (Em), and myogenic tone in skeletal mus...
متن کاملAsynchronous Ca Waves in Intact Venous Smooth Muscle
The rabbit inferior vena cava (IVC) is a large-capacitance vessel that displays typical contractile dose-response curves for caffeine and phenylephrine (PE). Using confocal microscopy on the endothelium-denuded IVC, we undertook experiments to correlate these whole-tissue contractile dose-response curves with changes in subcellular [Ca]i signals in the in situ vascular smooth muscle cells (VSMC...
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In canine bronchial smooth muscle (BSM), spasmogens evoke oscillations in membrane potential ("slow waves"). The depolarizing phase of the slow waves is mediated by voltage-dependent Ca2+ channels; we examined the roles played by Cl- and K+ currents and Na+-K+-ATPase activity in mediating the repolarizing phase. Slow waves were evoked using tetraethylammonium (25 mM) in the presence or absence ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2009
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.23.1_supplement.767.8